Improving Health and Health Care Using Real-World Evidence

 

The Trilogue Center for Real-World Evidence provides access to a variety of data sources, study designs, team building, and other supports to help researchers carry out the studies we need for improving health and healthcare in our community.

Aggregate Query Projects

Rapid cycle data summaries compiled across multiple institutions

Observational Studies

Detailed statistical analyses of health information such as EHR and survey data

Pragmatic Trials

Rigorous intervention studies integrated with care delivery and minimizing participant burden

Patient Engagement Support

Resources to help the development and function of engaged research teams

Our team is the University of Pittsburgh component of the PaTH Clinical Research Network, a Partner Network in PCORnet®, the National Patient-Centered Clinical Research Network. PCORnet® has been developed with funding from the Patient-Centered Outcomes Research Institute® (PCORI®). PCORnet® is a national resource where health data, research expertise, and patient insights are available to deliver fast, trustworthy answers that advance health outcomes. PCORnet® offers access to health record data on ~66 million patients across the US, as well as a variety of other resources to make research using RWE more efficient and patient-centered. PaTH is a regional partnership including the University of Pittsburgh/UPMC (lead site), Geisinger Health, Johns Hopkins University/Johns Hopkins Health System, Penn State College of Medicine/Milton S. Hershey Medical Center, Lewis Katz School of Medicine at Temple University/ Temple Health System/, The Ohio State University/Wexner Medical Center, RUSH, Boston Medical Center, and the University of Michigan/Michigan Medicine. PaTH-affiliated research includes dozens of observational studies and clinical trials.

The Trilogue team is happy to help you navigate and make connections with PCORnet® and PaTH to use these resources in your research. We support a variety of study types – please contact us to learn more.

Patient Engagement

MyPaTH Story Booth is a unique outreach effort to support engaged health research by connecting potential patient partners with researchers through the patients’ health narratives. As of March 2025, the Story Booth archive includes over 1,300 unique stories.
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